In a large skillet over medium heat, cook the ground beef and chopped onion until the beef is browned and the onion is softened, breaking up the meat with a spatula as it cooks.
Drain any excess grease from the skillet, if needed.
Add the chopped dill pickle slices to the skillet with the cooked beef and onion. Stir to combine.
In a small bowl, whisk together the ketchup, yellow mustard, mayonnaise, Worcestershire sauce, white vinegar, garlic powder, and onion powder until well combined.
Pour the sauce mixture into the skillet with the beef mixture. Stir to coat the beef evenly with the sauce.
Cook the mixture over medium heat for 5-7 minutes, or until heated through and slightly thickened. Season with salt and pepper to taste.
While the mixture is cooking, toast the hamburger buns if desired.
To serve, spoon the Big Mac Sloppy Joe mixture onto the bottom halves of the hamburger buns. Top with shredded lettuce and a slice of American cheese, if desired. Place the top halves of the buns over the filling.
Optionally, sprinkle sesame seeds over the top of the assembled sandwiches for a garnish.
Serve the Big Mac Sloppy Joes immediately, and enjoy this delicious twist on a classic fast food favorite!
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